PDK2 Protein (Myc-DYKDDDDK Tag)
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- Target See all PDK2 Proteins
- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PDK2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PDK2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PDK2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
- Alternative Name
- Pdk2 (PDK2 Products)
- Synonyms
- PDHK2 Protein, PDKII Protein, Pdk Protein, zgc:56209 Protein, PDK2 Protein, pyruvate dehydrogenase kinase 2 Protein, pyruvate dehydrogenase kinase, isoenzyme 2 Protein, pyruvate dehydrogenase kinase, isozyme 2b Protein, PDK2 Protein, Pdk2 Protein, pdk2b Protein
- Background
- This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Molecular Weight
- 46 kDa
- NCBI Accession
- NP_002602
- Pathways
- PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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