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PDGFC Protein (Transcript Variant 1)

PDGFC Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
Catalog No. ABIN2728542
  • Target See all PDGFC Proteins
    PDGFC (Platelet-Derived Growth Factor C (PDGFC))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 9
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human PDGFC (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 15-20 ng/ml.
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    Discover our top product PDGFC Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handling Advice
    Resuspend the protein in the desired concentration in proper buffer
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PDGFC (Platelet-Derived Growth Factor C (PDGFC))
    Alternative Name
    Pdgfc (PDGFC Products)
    Synonyms
    SCDGF Protein, FALLOTEIN Protein, 1110064L01Rik Protein, AI647969 Protein, PDGF-C Protein, platelet derived growth factor C Protein, platelet-derived growth factor, C polypeptide Protein, PDGFC Protein, Pdgfc Protein
    Target Type
    Viral Protein
    Background
    The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.
    Molecular Weight
    25 kDa
    NCBI Accession
    NP_057289
    Pathways
    RTK Signaling, Platelet-derived growth Factor Receptor Signaling
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