PCMT1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728412

Product Details

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PCMT1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PCMT1 / PIMT protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Alternative Name: Pcmt1,pimt (PCMT1 Products)

Synonyms: PIMT Protein, C79501 Protein, PCM Protein, PCMT Protein, etID309741.20 Protein, fj13d06 Protein, pimt Protein, wu:fj13d06 Protein, protein-L-isoaspartate (D-aspartate) O-methyltransferase Protein, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 Protein, protein-L-isoaspartate (D-aspartate) O-methyltransferase L homeolog Protein, protein-L-isoaspartate(D-aspartate)O-methyltransferase Protein, PCMT1 Protein, Pcmt1 Protein, pcmt1.L Protein, pcmt1 Protein, pcmt Protein

Background: This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 30.1 kDa

NCBI Accession: NP_005380

Pathways: Ribonucleoprotein Complex Subunit Organization