PCDHA4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
-
- Target See all PCDHA4 Proteins
- PCDHA4 (Protocadherin alpha 4 (PCDHA4))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PCDHA4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human PCDHA4 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PCDHA4 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- PCDHA4 (Protocadherin alpha 4 (PCDHA4))
- Alternative Name
- Pcdha4 (PCDHA4 Products)
- Synonyms
- CNR1 Protein, CNRN1 Protein, CRNR1 Protein, PCDH-ALPHA4 Protein, Cnr1 Protein, Crnr1 Protein, R75250 Protein, PCDHA4 Protein, CNRv4 Protein, Pcdha4 Protein, protocadherin alpha 4 Protein, protocadherin alpha-4 Protein, PCDHA4 Protein, Pcdha4 Protein, LOC100713594 Protein, LOC100629843 Protein
- Background
- This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
- Molecular Weight
- 82.9 kDa
- NCBI Accession
- NP_113688
-