HRPT2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728223

Product Details

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This HRPT2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Parafibromin protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Alternative Name: Parafibromin (CDC73 Products)

Synonyms: C1orf28 Protein, HPTJT Protein, HRPT2 Protein, HYX Protein, 8430414L16Rik Protein, BC027756 Protein, C130030P16Rik Protein, C81219 Protein, Hrpt2 Protein, hrpt2 Protein, zgc:63956 Protein, MGC108428 Protein, cdc73 Protein, LOC100222932 Protein, cell division cycle 73 Protein, cell division cycle 73, Paf1/RNA polymerase II complex component Protein, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) Protein, parafibromin Protein, cell division cycle 73 S homeolog Protein, CDC73 Protein, Cdc73 Protein, cdc73 Protein, Tsp_03925 Protein, Tsp_04052 Protein, Tsp_04125 Protein, cdc73.S Protein

Background: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3&apos mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Molecular Weight: 60.4 kDa

NCBI Accession: NP_078805

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance