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PAK6 Protein (Transcript Variant 1)

PAK6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
Catalog No. ABIN2728179
  • Target See all PAK6 Proteins
    PAK6 (P21-Activated Kinase 6 (PAK6))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human PAK6 (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Purity
    > 90 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Specific activity was determined as 2,086 pmoles/min/μg, according to the Zlyte assay protocol
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    Discover our top product PAK6 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PAK6 (P21-Activated Kinase 6 (PAK6))
    Alternative Name
    Pak6 (PAK6 Products)
    Synonyms
    PAK5 Protein, 4732456M09 Protein, pak6 Protein, si:ch211-158b22.3 Protein, p21 (RAC1) activated kinase 6 Protein, p21 protein (Cdc42/Rac)-activated kinase 6 Protein, p21 protein (Cdc42/Rac)-activated kinase 6b Protein, PAK6 Protein, Pak6 Protein, pak6b Protein
    Background
    This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    34.2 kDa
    NCBI Accession
    NP_064553
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