PAK2 Protein
PAK2
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 % as determined by SDS-PAGE and Coomassie blue staining
AbP, Func, PI, STD
Active
1 image
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- Target See all PAK2 Proteins
- PAK2 (P21-Activated Kinase 2 (PAK2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human PAK2 protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 90 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Specific activity was determined as 85,806 pmoles/min/μg, according to the Zlyte assay protocol
- Top Product
- Discover our top product PAK2 Protein
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P21-Activated Kinase 2 (PAK2) (AA 131-230) protein (GST tag)
PAK2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
P21-Activated Kinase 2 (PAK2) (AA 227-524) protein (His tag)PAK2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PAK2 (P21-Activated Kinase 2 (PAK2))
- Alternative Name
- Pak2 (PAK2 Products)
- Background
- The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
- Molecular Weight
- 33.5 kDa
- NCBI Accession
- NP_002568
- Pathways
- MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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