PAICS Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728164

Product Details

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PAICS protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PAICS / ADE2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Alternative Name: Paics,ade2 (PAICS Products)

Synonyms: cb293 Protein, sb:cb293 Protein, wu:fa28a05 Protein, GB14262 Protein, DDBDRAFT_0218550 Protein, DDBDRAFT_0230088 Protein, DDB_0218550 Protein, DDB_0230088 Protein, AIRC Protein, AS Protein, ADE2 Protein, ADE2H1 Protein, PAIS Protein, Ade2h1 Protein, Airc Protein, ade2 Protein, airc Protein, paics Protein, pais Protein, 2610511I09Rik Protein, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase Protein, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase Protein, multifunctional protein ADE2 Protein, phosphoribosylaminoimidazole carboxylase Protein, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog Protein, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase Protein, PAICS Protein, paics Protein, LOC551966 Protein, Tsp_02239a Protein, Tsp_02239 Protein, CNE02500 Protein, purC/E Protein, Paics Protein, paics.2.L Protein

Background: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 46.9 kDa

NCBI Accession: NP_006443

Pathways: Chromatin Binding