PAFAH1B1 Protein (Myc-DYKDDDDK Tag)
-
- Target See all PAFAH1B1 Proteins
- PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PAFAH1B1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human PAFAH1B1 / LIS1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PAFAH1B1 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))
- Alternative Name
- Pafah1b1,lis1 (PAFAH1B1 Products)
- Synonyms
- LIS1 Protein, LIS2 Protein, MDCR Protein, MDS Protein, PAFAH Protein, LIS-1 Protein, Lis1 Protein, MMS10-U Protein, Mdsh Protein, Ms10u Protein, Pafaha Protein, lis2 Protein, mdcr Protein, mds Protein, pafah Protein, pafah1b1-b Protein, PAFAHA Protein, Lis1a Protein, platelet activating factor acetylhydrolase 1b regulatory subunit 1 Protein, platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 Protein, platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 Protein, platelet activating factor acetylhydrolase 1b regulatory subunit 1 L homeolog Protein, platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a Protein, platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b Protein, PAFAH1B1 Protein, Pafah1b1 Protein, pafah1b1.L Protein, pafah1b1a Protein, pafah1b1b Protein
- Background
- This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.
- Molecular Weight
- 46.5 kDa
- NCBI Accession
- NP_000421
- Pathways
- M Phase, Regulation of Cell Size
-