P2RY12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all P2RY12 Proteins
- P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This P2RY12 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human P2RY12 / P2Y12 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product P2RY12 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
- Alternative Name
- p2ry12,p2y12 (P2RY12 Products)
- Synonyms
- 2900079B22Rik Protein, 4921504D23Rik Protein, P2Y12 Protein, ADPG-R Protein, BDPLT8 Protein, HORK3 Protein, P2T(AC) Protein, P2Y(12)R Protein, P2Y(AC) Protein, P2Y(ADP) Protein, P2Y(cyc) Protein, SP1999 Protein, P2y12 Protein, purinergic receptor P2Y, G-protein coupled 12 Protein, purinergic receptor P2Y12 Protein, P2ry12 Protein, P2RY12 Protein
- Background
- The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
- Molecular Weight
- 39.3 kDa
- NCBI Accession
- NP_073625
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