Occludin Protein (OCLN) (Myc-DYKDDDDK Tag)
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- Target See all Occludin (OCLN) Proteins
- Occludin (OCLN)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Occludin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Occludin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product OCLN Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Occludin (OCLN)
- Alternative Name
- Occludin (OCLN Products)
- Synonyms
- AI503564 Protein, Ocl Protein, ocln Protein, oclnb Protein, tpmt Protein, OCLN Protein, wu:fd23h10 Protein, wu:fi13c01 Protein, zgc:113992 Protein, zgc:56359 Protein, BLCPMG Protein, occludin Protein, occludin S homeolog Protein, occludin a Protein, Ocln Protein, OCLN Protein, ocln.S Protein, ocln Protein, oclna Protein
- Background
- This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
- Molecular Weight
- 59 kDa
- NCBI Accession
- NP_002529
- Pathways
- Cell-Cell Junction Organization, Hepatitis C
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