NXT1 Protein (Myc-DYKDDDDK Tag)
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- Target See all NXT1 Proteins
- NXT1 (NTF2-Related Export Protein 1 (NXT1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NXT1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NXT1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NXT1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NXT1 (NTF2-Related Export Protein 1 (NXT1))
- Alternative Name
- Nxt1 (NXT1 Products)
- Synonyms
- CG12752 Protein, DmNXT1 Protein, Dmel\\CG12752 Protein, Nxt Protein, dNxt Protein, dmNXT Protein, dmNXT1 Protein, dmP15 Protein, nxt1 Protein, p15 Protein, GB14514 Protein, MTR2 Protein, P15 Protein, 1110001N02Rik Protein, NTF2-related export protein 1 Protein, NTF2-related export protein Protein, nuclear transport factor 2 like export factor 1 Protein, nuclear transport factor 2-like export factor 1 Protein, Nxt1 Protein, LOC413378 Protein, Tsp_05214 Protein, NXT1 Protein
- Background
- The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
- Molecular Weight
- 15.7 kDa
- NCBI Accession
- NP_037380
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