NR0B1 Protein (Myc-DYKDDDDK Tag)
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- Target See all NR0B1 Proteins
- NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NR0B1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NR0B1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NR0B1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
- Alternative Name
- Nr0b1 (NR0B1 Products)
- Synonyms
- DAX Protein, NR0B1 Protein, dax1 Protein, AHC Protein, AHCH Protein, AHX Protein, DAX-1 Protein, DAX1 Protein, DSS Protein, GTD Protein, HHG Protein, NROB1 Protein, SRXY2 Protein, Ahc Protein, Ahch Protein, Dax1 Protein, nuclear receptor subfamily 0 group B member 1 Protein, nuclear receptor subfamily 0, group B, member 1 Protein, nuclear receptor subfamily 0 group B member 1 L homeolog Protein, NR0B1 Protein, nr0b1 Protein, nr0b1.L Protein, Nr0b1 Protein
- Background
- This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
- Molecular Weight
- 51.5 kDa
- NCBI Accession
- NP_000466
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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