Nicastrin Protein (NCSTN) (Myc-DYKDDDDK Tag)
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- Target See all Nicastrin (NCSTN) Proteins
- Nicastrin (NCSTN)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Nicastrin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Nicastrin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NCSTN Protein
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Nicastrin (NCSTN) (AA 1-689) protein (GST tag)
NCSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nicastrin (NCSTN) (AA 16-115) protein (GST tag)NCSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nicastrin (NCSTN) protein (His tag)NCSTN Origin: Mouse Host: HEK-293 Cells Recombinant > 99 % as determined by SDS-PAGE
Nicastrin (NCSTN) protein (Fc Tag)NCSTN Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Nicastrin (NCSTN)
- Alternative Name
- Nicastrin (NCSTN Products)
- Synonyms
- CG7012 Protein, Dmel\\CG7012 Protein, Nct Protein, Nic Protein, S5A Protein, ST96B Protein, agro Protein, dNct Protein, nic Protein, NCSTN Protein, DKFZp469O2418 Protein, APH2 Protein, 9430068N19Rik Protein, AA727311 Protein, Aph2 Protein, D1Dau13e Protein, Kiaa0253 Protein, mKIAA0253 Protein, nicastrin Protein, Nicastrin Protein, NCSTN Protein, nct Protein, ncstn Protein, CpipJ_CPIJ001617 Protein, Ncstn Protein, aph-2 Protein
- Background
- Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 75.2 kDa
- NCBI Accession
- NP_056146
- Pathways
- Notch Signaling, Neurotrophin Signaling Pathway
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