Nicastrin Protein (NCSTN) (Myc-DYKDDDDK Tag)
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- Target See all Nicastrin (NCSTN) Proteins
- Nicastrin (NCSTN)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Nicastrin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Nicastrin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NCSTN Protein
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Nicastrin (NCSTN) (AA 1-689) protein (GST tag)
NCSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nicastrin (NCSTN) protein (His tag)NCSTN Origin: Mouse Host: HEK-293 Cells Recombinant > 99 % as determined by SDS-PAGE
Nicastrin (NCSTN) protein (Fc Tag)NCSTN Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Nicastrin (NCSTN)
- Alternative Name
- Nicastrin (NCSTN Products)
- Background
- Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 75.2 kDa
- NCBI Accession
- NP_056146
- Pathways
- Notch Signaling, Neurotrophin Signaling Pathway
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