NFATC4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all NFATC4 Proteins
- NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NFATC4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NFATc4 / NFAT3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NFATC4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))
- Alternative Name
- Nfatc4,nfat3 (NFATC4 Products)
- Synonyms
- si:dkeyp-66d1.4 Protein, NFATC4 Protein, 3110041H08Rik Protein, AW107667 Protein, AW546455 Protein, Nfat3 Protein, NF-ATc4 Protein, NFAT3 Protein, nuclear factor of activated T-cells 4 Protein, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 Protein, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 Protein, NFATC4 Protein, nfatc4 Protein, Nfatc4 Protein
- Background
- This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 101.3 kDa
- NCBI Accession
- NP_001129494
- Pathways
- RTK Signaling, WNT Signaling
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