NEIL2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all NEIL2 Proteins
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NEIL2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NEIL2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NEIL2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
- Alternative Name
- Neil2 (NEIL2 Products)
- Synonyms
- NEH2 Protein, NEI2 Protein, Gm1212 Protein, nei like DNA glycosylase 2 Protein, nei like 2 (E. coli) Protein, NEIL2 Protein, Neil2 Protein
- Background
- NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM, Mar 2008].
- Molecular Weight
- 36.6 kDa
- NCBI Accession
- NP_001129218
- Pathways
- DNA Damage Repair
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