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Myosin VI Protein (MYO6) (Myc-DYKDDDDK Tag)

MYO6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2726687
  • Target See all Myosin VI (MYO6) Proteins
    Myosin VI (MYO6)
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Myosin VI protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MYO6 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MYO6 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Myosin VI (MYO6)
    Alternative Name
    Myo6 (MYO6 Products)
    Synonyms
    95F Protein, 95F MHC Protein, CG5695 Protein, Dm 95F Protein, Dm95F Protein, Dmel\\CG5695 Protein, Dro95F Protein, JAG Protein, Jaguar Protein, Jar Protein, M6 Protein, MHC95F Protein, MYOVI Protein, Mhc95F Protein, MyoVI Protein, Myosin VI Protein, jag Protein, ms(3)06746 Protein, myosins VI Protein, DFNA22 Protein, DFNB37 Protein, BC029719 Protein, Tlc Protein, sv Protein, RGD1560646 Protein, CMY6 Protein, jaguar Protein, myosin VI Protein, jar Protein, LOC373230 Protein, MYO6 Protein, myo6 Protein, Myo6 Protein
    Background
    This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molecular Weight
    148.5 kDa
    NCBI Accession
    NP_004990
    Pathways
    Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization
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