Myosin VI Protein (MYO6) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2726687

Product Details

Target: Myosin VI (MYO6)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Myosin VI protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human MYO6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Myosin VI (MYO6)

Alternative Name: Myo6 (MYO6 Products)

Synonyms: 95F Protein, 95F MHC Protein, CG5695 Protein, Dm 95F Protein, Dm95F Protein, Dmel\\CG5695 Protein, Dro95F Protein, JAG Protein, Jaguar Protein, Jar Protein, M6 Protein, MHC95F Protein, MYOVI Protein, Mhc95F Protein, MyoVI Protein, Myosin VI Protein, jag Protein, ms(3)06746 Protein, myosins VI Protein, DFNA22 Protein, DFNB37 Protein, BC029719 Protein, Tlc Protein, sv Protein, RGD1560646 Protein, CMY6 Protein, jaguar Protein, myosin VI Protein, jar Protein, LOC373230 Protein, MYO6 Protein, myo6 Protein, Myo6 Protein

Background: This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 148.5 kDa

NCBI Accession: NP_004990

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization