MR1 Protein (Myc-DYKDDDDK Tag)
MR1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
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- Target See all MR1 Proteins
- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MR1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MR1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MR1 Protein
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Major Histocompatibility Complex, Class I-Related (MR1) (AA 201-300) protein (GST tag)
MR1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
- Alternative Name
- Mr1 (MR1 Products)
- Synonyms
- YFV Protein, hlals Protein, MGC154362 Protein, MR1 Protein, DKFZp468C1823 Protein, HLALS Protein, H2ls Protein, Hlals Protein, MHC class I antigen YF5 Protein, major histocompatibility complex, class I-related Protein, major histocompatibility complex, class I-related L homeolog Protein, YF5 Protein, MR1 Protein, mr1.L Protein, mr1 Protein, Mr1 Protein
- Background
- MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
- Molecular Weight
- 39.2 kDa
- NCBI Accession
- NP_001522
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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