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MKNK1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

MKNK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2726083
  • Target See all MKNK1 Proteins
    MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MKNK1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MKNK1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MKNK1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))
    Alternative Name
    Mknk1 (MKNK1 Products)
    Synonyms
    MNK1 Protein, MKNK1 Protein, zgc:171912 Protein, 2410048M24Rik Protein, Mnk1 Protein, MAPK signal-integrating kinase 1 Protein, mknk1 Protein, mnk1 Protein, MAP kinase interacting serine/threonine kinase 1 Protein, MAP kinase-interacting serine/threonine kinase 1 Protein, MAP kinase interacting serine/threonine kinase 1 S homeolog Protein, MKNK1 Protein, mknk1 Protein, Mknk1 Protein, mknk1.S Protein
    Background
    This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.
    Molecular Weight
    51.2 kDa
    NCBI Accession
    NP_003675
    Pathways
    MAPK Signaling, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor
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