HMGCS2 Protein (Myc-DYKDDDDK Tag)
-
- Target See all HMGCS2 Proteins
- HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HMGCS2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human mHMG-CoA synthase / HMGCS2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HMGCS2 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))
- Alternative Name
- Mhmg-Coa Synthase,hmgcs2 (HMGCS2 Products)
- Synonyms
- 1300002P16 Protein, mHS Protein, DDBDRAFT_0219349 Protein, DDBDRAFT_0219924 Protein, DDB_0219349 Protein, DDB_0219924 Protein, Hmgcs1 Protein, Mt3h3mg Protein, hmgCoA Protein, 3-hydroxy-3-methylglutaryl-CoA synthase 2 Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 Protein, hydroxymethylglutaryl-CoA synthase Protein, hydroxymethylglutaryl-coa synthase Protein, 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 Protein, HMGCS2 Protein, Hmgcs2 Protein, mvaS Protein, CNC05080 Protein, HMCS1 Protein, hgsA Protein, MFER_RS00425 Protein, LOC100285783 Protein, ECU10_0510 Protein, Eint_100450 Protein
- Background
- The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
- Molecular Weight
- 52.3 kDa
- NCBI Accession
- NP_005509
- Pathways
- Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha
-