Menin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all Menin (MEN1) Proteins
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Menin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Menin (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MEN1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
- Alternative Name
- Menin (MEN1 Products)
- Synonyms
- MEAI Protein, SCG2 Protein, menin Protein, meai Protein, scg2 Protein, AW045611 Protein, menin 1 Protein, menin 1 L homeolog Protein, multiple endocrine neoplasia I Protein, multiple endocrine neoplasia 1 Protein, MEN1 Protein, men1 Protein, men1.L Protein, Men1 Protein
- Background
- This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 67.3 kDa
- NCBI Accession
- NP_570711
- Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
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