Melanoma gp100 Protein (Myc-DYKDDDDK Tag)
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- Target See all Melanoma gp100 (PMEL) Proteins
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Melanoma gp100 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Melanoma gp100 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PMEL Protein
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Premelanosome Protein (PMEL) (AA 1-661) protein (GST tag)
PMEL Origin: Human Host: Wheat germ Recombinant WB, AP, AA, ELISA
Premelanosome Protein (PMEL) (AA 25-595) protein (Fc Tag)PMEL Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Premelanosome Protein (PMEL) (AA 25-467) protein (His-SUMO Tag)PMEL Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Premelanosome Protein (PMEL) (AA 25-467) protein (His tag)PMEL Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Alternative Name
- Melanoma Gp100 (PMEL Products)
- Background
- This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
- Molecular Weight
- 70.1 kDa
- NCBI Accession
- NP_008859
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