MAML1 Protein (Myc-DYKDDDDK Tag)
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- Target See all MAML1 Proteins
- MAML1 (Mastermind-Like 1 (MAML1))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MAML1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Mastermind-Like Protein 1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MAML1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MAML1 (Mastermind-Like 1 (MAML1))
- Alternative Name
- Mastermind-Like Protein 1 (MAML1 Products)
- Synonyms
- mam1 Protein, mam-1 Protein, xmam1 Protein, MAML1 Protein, AI644666 Protein, AW743257 Protein, D930008C07Rik Protein, Mam-1 Protein, Mam1 Protein, mKIAA0200 Protein, mastermind like transcriptional coactivator 1 L homeolog Protein, mastermind like transcriptional coactivator 1 Protein, mastermind like 1 (Drosophila) Protein, mastermind-like transcriptional coactivator 1 Protein, maml1.L Protein, MAML1 Protein, Maml1 Protein
- Background
- This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
- Molecular Weight
- 107.9 kDa
- NCBI Accession
- NP_055572
- Pathways
- Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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