MAP2K7 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725395

Product Details

Target: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MAP2K7 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human MAP2K7 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Alternative Name: Map2k7 (MAP2K7 Products)

Synonyms: MAP2K7 Protein, 2 Protein, JNKK Protein, Jnkk2 Protein, Mapkk7 Protein, Mek7 Protein, Mkk7 Protein, MAPKK7 Protein, MKK7 Protein, PRKMK7 Protein, SAPKK-4 Protein, SAPKK4 Protein, 5930412N11Rik Protein, JNKK 2 Protein, MAPKK 7 Protein, MEK 7 Protein, Prkmk7 Protein, sek2 Protein, si:ch211-254d18.2 Protein, map2k7-A Protein, mitogen-activated protein kinase kinase 7 Protein, mitogen activated protein kinase kinase 7 Protein, mitogen-activated protein kinase kinase 7 L homeolog Protein, MAP2K7 Protein, Map2k7 Protein, map2k7 Protein, map2k7.L Protein

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

Molecular Weight: 47.3 kDa

NCBI Accession: NP_660186

Pathways: MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling