MAP2K4 Protein (Myc-DYKDDDDK Tag)
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- Target See all MAP2K4 Proteins
- MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MAP2K4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MAP2K4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MAP2K4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
- Alternative Name
- Map2k4 (MAP2K4 Products)
- Synonyms
- JNKK Protein, JNKK1 Protein, MAPKK4 Protein, MEK4 Protein, MKK4 Protein, PRKMK4 Protein, SAPKK-1 Protein, SAPKK1 Protein, SEK1 Protein, SERK1 Protein, SKK1 Protein, Sek1 Protein, Serk1 Protein, MKK4A-l Protein, map2k4 Protein, zgc:136500 Protein, jnkk Protein, mek4 Protein, mkk4 Protein, sek1 Protein, jnkk1 Protein, serk1 Protein, xmek2 Protein, mapkk4 Protein, prkmk4 Protein, 142758_at Protein, CG9738 Protein, CT27508 Protein, D-MKK4 Protein, DMKK4 Protein, Dmel\\CG9738 Protein, JNKK2 Protein, Mpk4 Protein, SEK1/MKK4 Protein, dMKK4 Protein, dMkk4 Protein, hep Protein, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 Protein, ATMEK4 Protein, ATMKK4 Protein, F19C24.26 Protein, F19C24_26 Protein, MAP KINASE KINASE 4 Protein, mitogen-activated protein kinase kinase 4 Protein, MKK4B Protein, zgc:194486 Protein, mitogen-activated protein kinase kinase 4 Protein, mitogen-activated protein kinase kinase 4a Protein, MAP kinase kinase 4 Protein, mitogen activated protein kinase kinase 4 Protein, mitogen-activated protein kinase kinase 4b Protein, MAP2K4 Protein, Map2k4 Protein, map2k4a Protein, map2k4 Protein, Mkk4 Protein, MKK4 Protein, map2k4b Protein
- Background
- This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 44.1 kDa
- NCBI Accession
- NP_003001
- Pathways
- MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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