MAL Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)
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- Target See all MAL Proteins
- MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant B
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MAL protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MAL (transcript variant b) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MAL Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))
- Alternative Name
- Mal (MAL Products)
- Synonyms
- AI326936 Protein, Bp50 Protein, GP39 Protein, HIGM1 Protein, IGM Protein, IMD3 Protein, T-BAM Protein, TRAP Protein, Tnfrsf5 Protein, p50 Protein, Mpv17 Protein, Vip17 Protein, mal Protein, wyatt Protein, MALGENE Protein, im:7142606 Protein, zgc:112003 Protein, mal, T-cell differentiation protein Protein, CD40 antigen Protein, myelin and lymphocyte protein, T cell differentiation protein Protein, myelin and lymphocyte protein Protein, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog Protein, MAL Protein, Cd40 Protein, Mal Protein, LOC100135389 Protein, mal Protein, tirap.L Protein
- Background
- The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.
- Molecular Weight
- 11.9 kDa
- NCBI Accession
- NP_071883
- Pathways
- Asymmetric Protein Localization
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