Lipin 1 Protein (LPIN1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724880

Product Details

Target: Lipin 1 (LPIN1)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Lipin 1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human LPIN1 / Lipin-1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Lipin 1 (LPIN1)

Alternative Name: Lpin1,lipin-1 (LPIN1 Products)

Synonyms: LPIN1 Protein, pap1 Protein, PAP1 Protein, 4631420P06 Protein, Kiaa0188 Protein, Lipin1 Protein, fld Protein, mKIAA0188 Protein, zgc:194552 Protein, zgc:194558 Protein, lipin1 Protein, lipin 1 Protein, phosphatidate phosphatase LPIN1 Protein, LPIN1 Protein, lpin1 Protein, LOC100539289 Protein, Lpin1 Protein

Background: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.

Molecular Weight: 98.5 kDa

NCBI Accession: NP_663731

Pathways: Monocarboxylic Acid Catabolic Process