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LPIN3 Protein (Myc-DYKDDDDK Tag)

LPIN3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724799
  • Target See all LPIN3 Proteins
    LPIN3 (Lipin 3 (LPIN3))
    Protein Type
    Recombinant
    Origin
    • 1
    • 1
    Human
    Source
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This LPIN3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Lipin 3 (LPIN3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product LPIN3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    LPIN3 (Lipin 3 (LPIN3))
    Abstract
    LPIN3 Products
    Synonyms
    MGC82840 Protein, LPIN3 Protein, DKFZp469D075 Protein, LIPN3L Protein, SMP2 Protein, dJ450M14.2 Protein, dJ450M14.3 Protein, dJ620E11.2 Protein, 9130206L11Rik Protein, AA438110 Protein, AV236139 Protein, mKIAA4023 Protein, lipin 3 L homeolog Protein, lipin 3 Protein, lpin3.L Protein, LPIN3 Protein, LOAG_08747 Protein, lpin3 Protein, Lpin3 Protein
    Background
    The protein encoded by this gene is a member of the lipin family of proteins, and all family members share strong homology in their C-terminal region. This protein is thought to form hetero-oligomers with other lipin family members, while one family member, lipin 1, can also form homo-oligomers. This protein contains conserved motifs for phosphatidate phosphatase 1 (PAP1) activity as well as a domain that interacts with a transcriptional co-activator. Lipin complexes act in the cytoplasm to catalyze the dephosphorylation of phosphatidic acid to produce diacylglycerol, which is the precursor of both triglycerides and phospholipids. Lipin complexes are also thought to regulate gene expression as transcriptional co-activators in the nucleus. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    93.4 kDa
    NCBI Accession
    NP_075047
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