Kallikrein 6 Protein (KLK6) (Transcript Variant B) (Myc-DYKDDDDK Tag)
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- Target See all Kallikrein 6 (KLK6) Proteins
- Kallikrein 6 (KLK6)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant B
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Kallikrein 6 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human KLK6 / Kallikrein-6 (transcript variant B) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product KLK6 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Kallikrein 6 (KLK6)
- Alternative Name
- Klk6,kallikrein-6 (KLK6 Products)
- Synonyms
- Bssp Protein, Klk7 Protein, PRSS18 Protein, PRSS9 Protein, SP59 Protein, hK6 Protein, Prss9 Protein, AI849898 Protein, BSP Protein, Klk29 Protein, MSP Protein, Prss18 Protein, neurosin Protein, kallikrein related peptidase 6 Protein, kallikrein related-peptidase 6 Protein, kallikrein-6 Protein, KLK6 Protein, Klk6 Protein, LOC100716801 Protein
- Background
- This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer&aposs and Parkinson&aposs disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- Molecular Weight
- 25.1 kDa
- NCBI Accession
- NP_001012982
- Pathways
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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