KLHL3 Protein (Myc-DYKDDDDK Tag)
KLHL3
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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- Target See all KLHL3 Proteins
- KLHL3 (Kelch-Like 3 (KLHL3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This KLHL3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human KLHL3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product KLHL3 Protein
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Kelch-Like 3 (KLHL3) (AA 1-301) protein (GST tag)
KLHL3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Kelch-Like 3 (KLHL3) (AA 1-65) protein (GST tag)KLHL3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- KLHL3 (Kelch-Like 3 (KLHL3))
- Alternative Name
- Klhl3 (KLHL3 Products)
- Synonyms
- 7530408C15Rik Protein, AI430941 Protein, EG627648 Protein, PHA2D Protein, RGD1565218 Protein, kelch like family member 3 Protein, kelch-like 3 Protein, kelch-like family member 3 Protein, KLHL3 Protein, Klhl3 Protein
- Background
- This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D) a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molecular Weight
- 64.8 kDa
- NCBI Accession
- NP_059111
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