KIRREL2 Protein (His tag)
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- Target See all KIRREL2 Proteins
- KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This KIRREL2 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human KIRREL2 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product KIRREL2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))
- Alternative Name
- Kirrel2 (KIRREL2 Products)
- Synonyms
- nlg1 Protein, neph3 Protein, filtrin Protein, FILTRIN Protein, NEPH3 Protein, NLG1 Protein, C330019F22Rik Protein, cb33 Protein, kirrel3 Protein, sb:cb33 Protein, si:dkey-29g23.1 Protein, wu:fb74e02 Protein, kirre like nephrin family adhesion molecule 2 Protein, kin of IRRE like 2 (Drosophila) Protein, kirre like nephrin family adhesion molecule 3, like Protein, kirrel2 Protein, KIRREL2 Protein, Kirrel2 Protein, kirrel3l Protein
- Background
- This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.
- Molecular Weight
- 66.9 kDa
- NCBI Accession
- NP_115499
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