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Kallikrein 8 Protein (KLK8) (DYKDDDDK Tag)

KLK8 Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723969
  • Target See all Kallikrein 8 (KLK8) Proteins
    Kallikrein 8 (KLK8)
    Protein Type
    Recombinant
    Origin
    • 8
    • 4
    • 3
    Human
    Source
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Insect cells (Sf9)
    Purification tag / Conjugate
    This Kallikrein 8 protein is labelled with DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Kallikrein-related peptidase 8 (KLK8), transcript variant 1, residues 33-260aa, with C-terminal DDK tag, expressed in sf9 cells. (C-term DDK tag, transcript variant 1) protein expressed in Sf9 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KLK8 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    50 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Kallikrein 8 (KLK8)
    Alternative Name
    Kallikrein-Related Peptidase 8 (Klk8) (KLK8 Products)
    Synonyms
    HNP Protein, NP Protein, NRPN Protein, PRSS19 Protein, TADG14 Protein, bsp1 Protein, KLK8 Protein, BSP1 Protein, Nrpn Protein, Prss19 Protein, kallikrein related peptidase 8 Protein, kallikrein related-peptidase 8 Protein, KLK8 Protein, Klk8 Protein
    Background
    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
    Molecular Weight
    25 kDa
    NCBI Accession
    NP_007187
    Pathways
    Complement System
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