Kallikrein 8 Protein (KLK8) (DYKDDDDK Tag)
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- Target See all Kallikrein 8 (KLK8) Proteins
- Kallikrein 8 (KLK8)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Insect cells (Sf9)
- Purification tag / Conjugate
- This Kallikrein 8 protein is labelled with DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Kallikrein-related peptidase 8 (KLK8), transcript variant 1, residues 33-260aa, with C-terminal DDK tag, expressed in sf9 cells. (C-term DDK tag, transcript variant 1) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product KLK8 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Kallikrein 8 (KLK8)
- Alternative Name
- Kallikrein-Related Peptidase 8 (Klk8) (KLK8 Products)
- Synonyms
- HNP Protein, NP Protein, NRPN Protein, PRSS19 Protein, TADG14 Protein, bsp1 Protein, KLK8 Protein, BSP1 Protein, Nrpn Protein, Prss19 Protein, kallikrein related peptidase 8 Protein, kallikrein related-peptidase 8 Protein, KLK8 Protein, Klk8 Protein
- Background
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 25 kDa
- NCBI Accession
- NP_007187
- Pathways
- Complement System
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