IRF1 Protein (Myc-DYKDDDDK Tag)
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- Target See all IRF1 Proteins
- IRF1 (Interferon Regulatory Factor 1 (IRF1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IRF1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human IRF1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IRF1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- IRF1 (Interferon Regulatory Factor 1 (IRF1))
- Alternative Name
- Irf1 (IRF1 Products)
- Synonyms
- irf1 Protein, zgc:136945 Protein, IRF1 Protein, irf11 Protein, zgc:103566 Protein, IRF-1 Protein, MAR Protein, AU020929 Protein, Irf-1 Protein, interferon regulatory factor 1 Protein, interferon regulatory factor 1a Protein, interferon regulatory factor 1b Protein, IRF1 Protein, irf1a Protein, irf1b Protein, Irf1 Protein
- Background
- IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
- Molecular Weight
- 36.3 kDa
- NCBI Accession
- NP_002189
- Pathways
- Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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