ILK Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all ILK Proteins
- ILK (Integrin-Linked Kinase (ILK))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ILK protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Integrin-linked protein kinase (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ILK Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response." in: The EMBO journal, Vol. 32, Issue 10, pp. 1409-24, (2013) (PubMed).
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Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response." in: The EMBO journal, Vol. 32, Issue 10, pp. 1409-24, (2013) (PubMed).
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- Target
- ILK (Integrin-Linked Kinase (ILK))
- Alternative Name
- Integrin-Linked Protein Kinase (ILK Products)
- Synonyms
- CG10504 Protein, CT29478 Protein, DmILK Protein, Dmel\\CG10504 Protein, ILK Protein, ilk Protein, l(3)78Ca Protein, p59 Protein, AA511515 Protein, ESTM24 Protein, zgc:65842 Protein, ILK-1 Protein, ILK-2 Protein, P59 Protein, p59ILK Protein, Integrin linked kinase Protein, integrin linked kinase Protein, integrin linked kinase S homeolog Protein, integrin-linked protein kinase Protein, integrin-linked kinase Protein, Ilk Protein, ILK Protein, ilk.S Protein, CpipJ_CPIJ016644 Protein, Bm1_20815 Protein, Tsp_07213 Protein, Tsp_07224 Protein, Tsp_15354 Protein, ilk Protein
- Background
- This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 51.2 kDa
- NCBI Accession
- NP_001014794
- Pathways
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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