INSIG2 Protein (Myc-DYKDDDDK Tag)
-
- Target See all INSIG2 Proteins
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This INSIG2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human INSIG2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product INSIG2 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
- Alternative Name
- Insig2 (INSIG2 Products)
- Synonyms
- MGC82156 Protein, INSIG-2 Protein, 2900053I11Rik Protein, C730043J18Rik Protein, Insig-2 Protein, insulin induced gene 2 Protein, insulin induced gene 2 L homeolog Protein, insig2 Protein, insig2.L Protein, INSIG2 Protein, Insig2 Protein
- Background
- The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
- Molecular Weight
- 24.6 kDa
- NCBI Accession
- NP_057217
- Pathways
- ER-Nucleus Signaling
-