IL1RAP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723387

Product Details

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This IL1RAP protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human IL1RAP (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Alternative Name: Il1rap (IL1RAP Products)

Synonyms: IL1RAP Protein, il-1racp Protein, il-racp Protein, il1r3 Protein, C3orf13 Protein, IL-1RAcP Protein, IL1R3 Protein, 6430709H04Rik Protein, AI255955 Protein, AV239853 Protein, IL-1RAcp Protein, Il1racpb Protein, interleukin 1 receptor accessory protein Protein, IL1RAP Protein, il1rap Protein, il-1racp Protein, Il1rap Protein

Background: Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Molecular Weight: 40.8 kDa

NCBI Accession: NP_608273

Pathways: NF-kappaB Signaling, Growth Factor Binding