IDUA Protein (Myc-DYKDDDDK Tag)
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- Target See all IDUA Proteins
- IDUA (Iduronidase, alpha-L- (IDUA))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IDUA protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Alpha-L-iduronidase / IDUA protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IDUA Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- IDUA (Iduronidase, alpha-L- (IDUA))
- Alternative Name
- Iduronidase, alpha-L (Idua) (IDUA Products)
- Synonyms
- IDA Protein, MPS1 Protein, 6030426D08 Protein, alpha-L-iduronidase Protein, MGC80842 Protein, si:ch211-12e13.9 Protein, IDUA Protein, iduronidase, alpha-L- Protein, iduronidase, alpha-L- L homeolog Protein, alpha-L-iduronidase Protein, IDUA Protein, Idua Protein, idua.L Protein, idua Protein, LOC5564727 Protein
- Background
- This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).
- Molecular Weight
- 70 kDa
- NCBI Accession
- NP_000194
- Pathways
- Glycosaminoglycan Metabolic Process
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