HYAL1 Protein (Transcript Variant 5) (His tag)
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- Target See all HYAL1 Proteins
- HYAL1 (Hyaluronidase-1 (HYAL1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 5
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HYAL1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human HYAL1 / Hyaluronidase-1 (transcript variant 5) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Top Product
- Discover our top product HYAL1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Buffer
- Supplied as a 0.2 μM filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HYAL1 (Hyaluronidase-1 (HYAL1))
- Alternative Name
- Hyal1,hyaluronidase-1 (HYAL1 Products)
- Synonyms
- HYAL-1 Protein, LUCA1 Protein, NAT6 Protein, Hya1 Protein, Hyal-1 Protein, hyaluronoglucosaminidase 1 Protein, HYAL1 Protein, Hyal1 Protein
- Background
- This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 47.18kD
- NCBI Accession
- NP_695017
- Pathways
- Glycosaminoglycan Metabolic Process
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