HSCB Protein (Myc-DYKDDDDK Tag)
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- Target See all HSCB Proteins
- HSCB (HscB Iron-Sulfur Cluster Co-Chaperone Homolog (HSCB))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HSCB protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human HSCB / DNAJC20 / HSC20 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HSCB Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HSCB (HscB Iron-Sulfur Cluster Co-Chaperone Homolog (HSCB))
- Alternative Name
- Hscb,dnajc20,hsc20 (HSCB Products)
- Synonyms
- RGD1311005 Protein, DNAJC20 Protein, HSC20 Protein, JAC1 Protein, dJ366L4.2 Protein, AI325508 Protein, AW049829 Protein, Hsc20 Protein, HscB mitochondrial iron-sulfur cluster co-chaperone Protein, HscB mitochondrial iron-sulfur cluster cochaperone Protein, HscB iron-sulfur cluster co-chaperone Protein, Hscb Protein, HSCB Protein
- Background
- This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 27.2 kDa
- NCBI Accession
- NP_741999
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