GUCY2D Protein (Myc-DYKDDDDK Tag)
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- Target See all GUCY2D Proteins
- GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GUCY2D protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human GUCY2D / RETGC1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GUCY2D Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
- Alternative Name
- Gucy2d,retgc1 (GUCY2D Products)
- Synonyms
- GUCY2D Protein, CORD5 Protein, CORD6 Protein, CYGD Protein, GUC1A4 Protein, GUC2D Protein, LCA Protein, LCA1 Protein, RCD2 Protein, RETGC-1 Protein, ROS-GC1 Protein, ROSGC Protein, retGC Protein, guanylate cyclase 2D, retinal Protein, guanylate cyclase 2d Protein, GUCY2D Protein, Gucy2d Protein
- Background
- This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
- Molecular Weight
- 119.9 kDa
- NCBI Accession
- NP_000171
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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