GZMA Protein (Myc-DYKDDDDK Tag)
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- Target See all GZMA Proteins
- GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GZMA protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Granzyme A (GZMA) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GZMA Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
- Alternative Name
- Granzyme A (Gzma) (GZMA Products)
- Synonyms
- gzmA Protein, GZMA Protein, AW494114 Protein, Ctla-3 Protein, Ctla3 Protein, Hf Protein, SE1 Protein, TSP-1 Protein, TSP1 Protein, CTLA3 Protein, HFSP Protein, granzyme A Protein, Granzyme A Protein, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) Protein, gzmA Protein, GZMA Protein, graa Protein, Gzma Protein
- Background
- Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface &aposnonself&apos antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
- Molecular Weight
- 28.8 kDa
- NCBI Accession
- NP_006135
- Pathways
- Apoptosis
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