GPT2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all GPT2 Proteins
- GPT2 (Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GPT2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human GPT2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GPT2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
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Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
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- Target
- GPT2 (Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2))
- Alternative Name
- Gpt2 (GPT2 Products)
- Synonyms
- ALT2 Protein, GPT2 Protein, im:7150662 Protein, sb:cb580 Protein, zgc:165657 Protein, Cc2-5 Protein, 4631422C05Rik Protein, AU014768 Protein, AU041193 Protein, C87201 Protein, ALANINE AMINOTRANSFERASE 2 Protein, AtAlaAT2 Protein, AtAlaATm Protein, T10D10.20 Protein, T10D10_20 Protein, alanine aminotransferase 2 Protein, glutamic--pyruvic transaminase 2 Protein, glutamic pyruvate transaminase (alanine aminotransferase) 2 L homeolog Protein, glutamic pyruvate transaminase (alanine aminotransferase) 2 Protein, alanine aminotransferase 2 Protein, GPT2 Protein, gpt2.L Protein, gpt2 Protein, PTRG_06494 Protein, Gpt2 Protein, ALAAT2 Protein
- Background
- This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 57.7 kDa
- NCBI Accession
- NP_597700
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