GNS Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2722117

Product Details

Target: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This GNS protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human GNS / G6S protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Alternative Name: Gns,g6s (GNS Products)

Synonyms: G6S Protein, 2610016K11Rik Protein, AU042285 Protein, C87209 Protein, N28088 Protein, NV14559 Protein, N-acetylglucosamine-6-sulfatase Protein, zgc:114066 Protein, gns Protein, wu:fi20h10 Protein, zgc:55370 Protein, glucosamine (N-acetyl)-6-sulfatase Protein, glucosamine (N-acetyl)-6-sulfatase S homeolog Protein, glucosamine (N-acetyl)-6-sulfatase a Protein, N-acetylglucosamine-6-sulfatase Protein, glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b Protein, GNS Protein, Gns Protein, gns.S Protein, gns Protein, gnsa Protein, CpipJ_CPIJ000745 Protein, Sros_7372 Protein, VDBG_04409 Protein, Halhy_3165 Protein, gnsb Protein

Background: The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

Molecular Weight: 58.3 kDa

NCBI Accession: NP_002067

Pathways: Glycosaminoglycan Metabolic Process