GATM Protein (Myc-DYKDDDDK Tag)
-
- Target See all GATM products
- GATM (Glycine Amidinotransferase (GATM))
- Protein Type
- Recombinant
- Origin
- Human
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GATM protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human Glycine amidinotransferase protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- GATM (Glycine Amidinotransferase (GATM))
- Alternative Name
- Glycine Amidinotransferase (GATM Products)
- Synonyms
- AGAT Protein, AT Protein, CCDS3 Protein, glycine amidinotransferase Protein, Glycine amidinotransferase Protein, BRAFLDRAFT_280917 Protein, Bmur_0416 Protein, GATM Protein
- Background
- This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
- Molecular Weight
- 44.2 kDa
- NCBI Accession
- NP_001473
-