GBA Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all GBA Proteins
- GBA (Glucosidase, Beta, Acid (GBA))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GBA protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Glucosylceramidase (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GBA Protein
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Glucosidase, Beta, Acid (GBA) (AA 362-512) protein (His-IF2DI Tag)
GBA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Glucosidase, Beta, Acid (GBA) (AA 431-536) protein (GST tag)GBA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glucosidase, Beta, Acid (GBA) (AA 1-536) protein (GST tag)GBA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glucosidase, Beta, Acid (GBA) (AA 146-235) protein (GST tag)GBA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glucosidase, Beta, Acid (GBA) (Transcript Variant 1) (Active) protein (Myc-DYKDDDDK Tag)GBA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GBA (Glucosidase, Beta, Acid (GBA))
- Alternative Name
- Glucosylceramidase (GBA Products)
- Synonyms
- GBA1 Protein, GCB Protein, GLUC Protein, BETA-GLUCOSIDASE Protein, T12J13.8 Protein, T12J13_8 Protein, beta glucosidase 25 Protein, PSPTO3318 Protein, PSPTO4290 Protein, GC Protein, GCase Protein, betaGC Protein, glucosylceramidase beta Protein, beta glucosidase 25 Protein, beta-glucosidase Protein, Beta-glucosidase Protein, glucosidase, beta, acid Protein, glucosylceramidase Protein, bglX-2 Protein, GBA Protein, BGLU25 Protein, PSPTO_3318 Protein, bglX Protein, bglA4 Protein, Gba Protein, LOC100399524 Protein, bglA.2 Protein, bglX-2 Protein
- Background
- This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 55.5 kDa
- NCBI Accession
- NP_001005742
- Pathways
- Cellular Glucan Metabolic Process
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