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GADD34 Protein (Myc-DYKDDDDK Tag)

PPP1R15A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721550
  • Target See all GADD34 (PPP1R15A) Proteins
    GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
    Protein Type
    Recombinant
    Origin
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This GADD34 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human GADD34 / PPP1R15A protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PPP1R15A Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
    Alternative Name
    Gadd34,ppp1r15a (PPP1R15A Products)
    Synonyms
    9630030H21 Protein, Gadd34 Protein, Myd116 Protein, GADD34 Protein, Peg-3 Protein, RGD1624209 Protein, protein phosphatase 1 regulatory subunit 15A Protein, protein phosphatase 1, regulatory (inhibitor) subunit 15A Protein, protein phosphatase 1, regulatory subunit 15A Protein, PPP1R15A Protein, Ppp1r15a Protein
    Background
    This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
    Molecular Weight
    73.3 kDa
    NCBI Accession
    NP_055145
    Pathways
    ER-Nucleus Signaling, Unfolded Protein Response
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