Frataxin Protein (FXN) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all Frataxin (FXN) Proteins
- Frataxin (FXN)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Frataxin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Frataxin (FXN) (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FXN Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Frataxin (FXN)
- Abstract
- FXN Products
- Synonyms
- zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein
- Background
- This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to > 90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 18.8 kDa
- NCBI Accession
- NP_000135
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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