FKBP5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all FKBP5 Proteins
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FKBP5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FKBP5 / FKBP51 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FKBP5 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
- Alternative Name
- Fkbp5,fkbp51 (FKBP5 Products)
- Synonyms
- FKBP5 Protein, FKBP-5 Protein, AIG6 Protein, FKBP51 Protein, FKBP54 Protein, P54 Protein, PPIase Protein, Ptg-10 Protein, D17Ertd592e Protein, Dit1 Protein, si:zc263a23.8 Protein, wu:fc31g11 Protein, wu:fl87b03 Protein, zgc:64082 Protein, FK506 binding protein 5 Protein, FKBP5 Protein, fkbp5 Protein, Fkbp5 Protein
- Background
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].
- Molecular Weight
- 51 kDa
- NCBI Accession
- NP_004108
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