FKBP1B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2721208

Product Details

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FKBP1B protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human FKBP1B / FKBP9 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Alternative Name: Fkbp1b,fkbp9 (FKBP1B Products)

Synonyms: FKBP12.6 Protein, MGC68829 Protein, FKBP1B Protein, DKFZp459K1429 Protein, 12.6kDa Protein, AW494148 Protein, calstabin2 Protein, FKBP1L Protein, OTK4 Protein, PKBP1L Protein, PPIase Protein, FK506 binding protein 1B Protein, FK506 binding protein 1B L homeolog Protein, FK506 binding protein 1b Protein, FKBP1B Protein, fkbp1b.L Protein, fkbp1b Protein, Fkbp1b Protein

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.

Molecular Weight: 8.6 kDa

NCBI Accession: NP_473374

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity