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Fibromodulin Protein (FMOD) (Myc-DYKDDDDK Tag)

FMOD Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721165
  • Target See all Fibromodulin (FMOD) Proteins
    Fibromodulin (FMOD)
    Protein Type
    Recombinant
    Origin
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Fibromodulin protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Fibromodulin protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FMOD Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Adini, Adini, Bazinet, Watnick, Bielenberg, DAmato: "Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, (2014) (PubMed).

  • Target
    Fibromodulin (FMOD)
    Alternative Name
    Fibromodulin (FMOD Products)
    Synonyms
    FMOD Protein, AI131919 Protein, AU041740 Protein, SLRR2E Protein, LOC100286414 Protein, sc:d0415 Protein, si:dkey-31j12.4 Protein, LOC100229381 Protein, FM Protein, fibromodulin Protein, fibromodulin b Protein, FMOD Protein, Fmod Protein, LOC100286414 Protein, fmodb Protein
    Background
    Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    41.2 kDa
    NCBI Accession
    NP_002014
    Pathways
    Glycosaminoglycan Metabolic Process
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